![]() The diagnosis of abnormal paroxysmal motor events in sleep presents a particular challenge for the clinician. This may reduce the requirement for tertiary referral and extensive inpatient monitoring. Results Nocturnal frontal lobe epilepsy was correctly diagnosed from the FLEP score in 31 of 31 patients, with a sensitivity of 1.0 (95% confidence interval, 0.85-1.00), specificity of 0.90 (95% CI, 0.73-0.97), positive predictive value of 0.91 (95% CI, 0.75-0.97), and negative predictive value of 1.00 (95% CI, 0.85-1.00).Ĭonclusions A diagnosis of NFLE can be made reliably using the clinical features identified in the FLEP scale. Main Outcome Measure The diagnosis obtained from scores on the FLEP scale was compared with the confirmed diagnosis in each patient. Intervention Two independent interviews were conducted in each case, with the patient and a witness, by researchers blinded to the diagnosis. Participants Sixty-two patients (45 men) with paroxysmal nocturnal events. Setting Patients were recruited after appropriate diagnostic workup in tertiary sleep and epilepsy referral centers in Melbourne, Australia. It was then validated in a sample of individuals with firmly diagnosed nocturnal events. Objective To examine the reliability of the clinical history in diagnosing NFLE, using the Frontal Lobe Epilepsy and Parasomnias (FLEP) scale.ĭesign The FLEP scale, comprising specific questions reflecting the diagnostic features of NFLE and parasomnias, was developed by an expert panel following review of the literature. In nocturnal frontal lobe epilepsy (NFLE), the unusual seizure features often lead to diagnostic confusion with nonepileptic parasomnias video-electroencephalography monitoring is usually required to make the diagnosis. ![]() Shared Decision Making and Communicationīackground Abnormal paroxysmal events in sleep may be parasomnias or epileptic seizures. ![]()
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